MARS
MARS - Molecular Diagnosis and Risk Stratification of Sepsis...
Description
MARS is a multicenter prospective cohort of ICU patients aimed at developing new molecular technologies for early diagnosis and risk stratification of sepsis....
General Design
- Type
- Biobank, Cohort study
- Cohort type
- Clinical cohort
- Data collection type
- Prospective
- Design
- Longitudinal
- Design description
- Ongoing prospective cohort and biobank of ICU patients admitted to the UMC Utrecht since 2011. The AMC was a participating center between 2011 and 2013.
- Start/End data collection
- 2011 (ongoing)
Population
- Countries
- Netherlands (the)
- Regions
- Noord-Holland, Utrecht
- Number of participants
- 17000
- Population age groups
- Adult (18+ years)
- Main medical condition
- I Certain infectious and parasitic diseases
- A30-A49 Other bacterial diseases
- A41.9 Sepsis, unspecified
- Inclusion criteria
- Age group inclusion criterion
- Defined population inclusion criterion
- Health status inclusion criterion
- Hospital patient inclusion criterion
- Other inclusion criteria
- ICU admitted patients, with exception of elective cardiothoracic surgery patients.
Organisations
Lead organisations
- UMC Utrecht (UMCU)Netherlands (the)
Researcher
Additional organisations
- Amsterdam Medical Center (AMC)Netherlands (the)
Contributors
- prof. dr. O.L. (Olaf) CremerUMC Utrechto.l.cremer@umcutrecht.nl
Principal Investigator, Primary contact, Project manager, Project leader, Public lead
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Networks
Part of networks...
Publications
Electronic Implementation of a Novel Surveillance Paradigm for Ventilator-associated Events. Feasibility and Validation
Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis
Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study
Validation of a Novel Molecular Host Response Assay to Diagnose Infection in Hospitalized Patients Admitted to the ICU With Acute Respiratory Failure
Access conditions
Data and samples are accessible after permission of the principal investigator of the MARS cohort. In general, ethics approval is required for use of biobank samples (TCBio approval)....
- Data access conditions
- health or medical or biomedical research
- disease specific research
- Data use conditions
- research specific restrictions
- collaboration required
- ethics approval required
- project specific restriction
- Data access fee
- true
- Release type
- Closed dataset
- Prelinked
- false
- Linkage options
- The questionnaires sent out at 1 year after ICU discharge can be linked to the MARS database. These questionnaires contain data on quality of life and mental well-being at 1 year. Upon request, the MARS database can be enriched with additional healthcare data from the EPD.
Funding & Acknowledgements
- Funding
- The MARS cohort received a grant from the Center for Translational Molecular Medicine (http://www.ctmm.nl) project MARS (grant 04I-201).